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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRD4
All Species:
12.12
Human Site:
S647
Identified Species:
38.1
UniProt:
O60885
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60885
NP_055114.1
1362
152219
S647
R
E
P
S
L
K
N
S
N
P
D
E
I
E
I
Chimpanzee
Pan troglodytes
XP_512452
1148
127234
S647
R
T
P
P
F
F
F
S
N
Y
N
I
C
V
L
Rhesus Macaque
Macaca mulatta
XP_001115820
787
86976
I293
T
T
P
T
P
T
A
I
L
A
P
G
S
P
A
Dog
Lupus familis
XP_866354
726
80895
P230
H
P
F
P
P
V
T
P
D
L
I
V
Q
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESU6
1400
155905
S648
R
E
P
S
L
K
N
S
N
P
D
E
I
E
I
Rat
Rattus norvegicus
Q6MGA9
798
88032
G303
G
S
P
A
S
P
P
G
S
L
E
P
K
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025845
729
80371
T235
K
R
K
A
D
T
T
T
P
T
T
T
A
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13709
2038
205327
S989
R
E
P
S
L
R
D
S
N
P
D
E
I
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
31.2
51.8
N.A.
93.1
31.7
N.A.
N.A.
29.4
N.A.
N.A.
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
78.8
41.3
52.2
N.A.
94
41.4
N.A.
N.A.
39.8
N.A.
N.A.
N.A.
37
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
0
N.A.
100
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
13.3
6.6
N.A.
100
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
0
13
0
0
13
0
0
13
13
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
0
0
0
0
13
0
13
0
13
0
38
0
0
0
0
% D
% Glu:
0
38
0
0
0
0
0
0
0
0
13
38
0
38
0
% E
% Phe:
0
0
13
0
13
13
13
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
13
13
38
13
50
% I
% Lys:
13
0
13
0
0
25
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
0
38
0
0
0
13
25
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
25
0
50
0
13
0
0
0
0
% N
% Pro:
0
13
75
25
25
13
13
13
13
38
13
13
0
13
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
50
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
13
0
38
13
0
0
50
13
0
0
0
13
0
0
% S
% Thr:
13
25
0
13
0
25
25
13
0
13
13
13
0
13
0
% T
% Val:
0
0
0
0
0
13
0
0
0
0
0
13
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _